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Product info: General Health
Accutane (ISOTRETINOIN) is a drug used for the treatment of severe, disfiguring cystic acne that has not cleared up in response to milder medications such as antibiotics.
It works on the oil glands within the skin, shrinking them and diminishing their output. Accutane derives from vitamin A and is found in small quantities naturally in the body.

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Possible food and drug interactions when taking Accutane

While taking Accutane, do not take vitamin supplements containing vitamin A. Accutane and vitamin A are chemically related; taking them together is like taking an overdose of vitamin A.

The herb St. John's wort may interact with hormonal contraceptives (taken as part of iPLEDGE). Pregnancies have been reported by those patients who have used St. John's wort in combination with Accutane.

Remember, too, that Accutane should not be combined with tetracycline antibiotics such as doxycycline hyclate and minocycline.
Special information if you are pregnant or breastfeeding

Accutane causes birth defects; do not use it while pregnant. Nursing mothers should not take Accutane because of the possibility of passing the drug on to the baby via breast milk.
Recommended dosage for Accutane

The recommended dosage range for Accutane is 0.5 to 1 milligram per 2.2 pounds of body weight, divided into 2 doses daily, for 15 to 20 weeks. For very severe cases, the doctor may increase the daily dose to as much as 2 milligrams per 2.2 pounds.

If after a period of 2 months or more off therapy, severe cystic acne persists, your doctor may prescribe a second course of therapy.

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